Authors :
Usha Topalkatti; Frederick M. Tiesenga; Matthew Phillips; Vidushi Rajendra; Baridilo Kponi
Volume/Issue :
Volume 10 - 2025, Issue 4 - April
Google Scholar :
https://tinyurl.com/5ykbvmt9
Scribd :
https://tinyurl.com/3zaccett
DOI :
https://doi.org/10.38124/ijisrt/25apr1854
Google Scholar
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Abstract :
Perforated sigmoid diverticulitis is a relatively uncommon but severe complication of diverticular disease, which
itself is a leading cause of gastrointestinal morbidity. Although diverticulosis is prevalent, particularly in the aging
population, perforation occurs in a smaller subset of cases and presents significant clinical challenges. This case report offers
a thorough examination of the epidemiology, pathophysiology, clinical features, diagnostic techniques, and surgical
management of perforated sigmoid diverticulitis. The condition most frequently affects middle-aged to older adults, with a
bimodal age distribution that includes both the elderly and younger individuals with risk factors such as obesity, smoking,
and low-fiber diets. The pathogenesis is characterized by increased intraluminal pressure within the diverticula, resulting in
mucosal perforation, bacterial infiltration, and peritoneal inflammation. Symptoms typically include acute left lower
quadrant pain, fever, and systemic signs of infection, although some patients may present with more subtle manifestations
without overt signs of peritoneal irritation. Diagnostic assessment is largely reliant on advanced imaging techniques, with
CT scanning considered the gold standard for confirming the diagnosis, revealing bowel wall thickening, fat stranding, and
extraluminal gas. Additional laboratory tests, such as a complete blood count and inflammatory markers, are used to support
the diagnosis and guide treatment. Surgical intervention is the primary treatment approach, with options ranging from
resection with primary anastomosis, Hartmann’s procedure, or laparoscopic surgery, depending on the severity of the
perforation and the patient's clinical status. The prognosis is closely linked to the timing of surgical intervention, and
potential postoperative complications such as abscess formation, sepsis, and anastomotic leaks require vigilant management.
This report aims to provide a deeper understanding of perforated sigmoid diverticulitis and emphasizes the importance of
early diagnosis, appropriate treatment strategies, and improved patient outcomes based on the latest clinical evidence.
Keywords :
Perforated Sigmoid Diverticulitis, Management Strategies, Exploratory Laparotomy, Sigmoidectomy with End Colostomy/Hartmann’s Procedure, Appendectomy.
References :
- Stollman NH, Raskin JB. Diagnosis and management of diverticular disease of the colon in adults. Ad Hoc Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol. 1999;94:3110–3121. doi: 10.1111/j.1572-0241.1999.01501.x.
- Woods RJ, Lavery IC, Fazio VW, Jagelman DG, Weakley FL. Internal fistulas in diverticular disease. Dis Colon Rectum. 1988;31:591–596. doi: 10.1007/BF02556792. [DOI] [PubMed] [Google Scholar]
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- Hanna MH, Kaiser AM. Update on the management of sigmoid diverticulitis. World J Gastroenterol. 2021 Mar 7;27(9):760-781. doi: 10.3748/wjg.v27.i9.760.
- Kiely MX, Yao M, Chen L. Laparoscopic Lavage in the Management of Hinchey III/IV Diverticulitis. Clin Colon Rectal Surg. 2021 Mar;34(2):104-112. doi: 10.1055/s-0040-1716702.
Perforated sigmoid diverticulitis is a relatively uncommon but severe complication of diverticular disease, which
itself is a leading cause of gastrointestinal morbidity. Although diverticulosis is prevalent, particularly in the aging
population, perforation occurs in a smaller subset of cases and presents significant clinical challenges. This case report offers
a thorough examination of the epidemiology, pathophysiology, clinical features, diagnostic techniques, and surgical
management of perforated sigmoid diverticulitis. The condition most frequently affects middle-aged to older adults, with a
bimodal age distribution that includes both the elderly and younger individuals with risk factors such as obesity, smoking,
and low-fiber diets. The pathogenesis is characterized by increased intraluminal pressure within the diverticula, resulting in
mucosal perforation, bacterial infiltration, and peritoneal inflammation. Symptoms typically include acute left lower
quadrant pain, fever, and systemic signs of infection, although some patients may present with more subtle manifestations
without overt signs of peritoneal irritation. Diagnostic assessment is largely reliant on advanced imaging techniques, with
CT scanning considered the gold standard for confirming the diagnosis, revealing bowel wall thickening, fat stranding, and
extraluminal gas. Additional laboratory tests, such as a complete blood count and inflammatory markers, are used to support
the diagnosis and guide treatment. Surgical intervention is the primary treatment approach, with options ranging from
resection with primary anastomosis, Hartmann’s procedure, or laparoscopic surgery, depending on the severity of the
perforation and the patient's clinical status. The prognosis is closely linked to the timing of surgical intervention, and
potential postoperative complications such as abscess formation, sepsis, and anastomotic leaks require vigilant management.
This report aims to provide a deeper understanding of perforated sigmoid diverticulitis and emphasizes the importance of
early diagnosis, appropriate treatment strategies, and improved patient outcomes based on the latest clinical evidence.
Keywords :
Perforated Sigmoid Diverticulitis, Management Strategies, Exploratory Laparotomy, Sigmoidectomy with End Colostomy/Hartmann’s Procedure, Appendectomy.