Synchronous Carcinoma Cervix with Renal Cell Carcinoma: An Incidental Finding


Authors : Dr. Mayank Soni; Dr. Shrutikant Bhatia; Dr. Dhiraj Gupta

Volume/Issue : Volume 9 - 2024, Issue 6 - June

Google Scholar : https://tinyurl.com/vwbajhsh

Scribd : https://tinyurl.com/y2fx5hap

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUN536

Abstract : Background In India, renal cell carcinoma (RCC) is the most frequent kidney cancer with an increasing tendency, whereas cervical cancer is the second most common disease among women. Synchronicity of RCC with other malignancies is not uncommon, but with the cervical cancer is rare.  Case description A 64-year-old, postmenopausal female, presented with complaint of bleeding per vagina and was diagnosed with carcinoma cervix and later on metastatic work-up also diagnosed with right RCC. After multidisciplinary discussion, patient planned for management for cervix then followed by renal lesion. Patient received radical external beam radiotherapy followed by brachytherapy for carcinoma cervix and underwent nephrectomy for right RCC.  Conclusion Synchronous cases of cervical cancer and renal cell carcinoma are very rare. Advancement in diagnostic protocol makes these kind of cases common and multidisciplinary team decisions are required for their management.

Keywords : Carcinoma Cervix, Multidisciplinary, Renal Cell Carcinoma (RCC), Synchronous.

References :

  1. Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2024 May;74(3):229-63.
  2. Sathishkumar K, Chaturvedi M, Das P, Stephen S, Mathur P. Cancer incidence estimates for 2022 & projection for 2025: result from National Cancer Registry Programme, India. Indian Journal of Medical Research. 2022 Oct 1;156(4&5):598-607.
  3. Takeda T, Sagae S, Koizumi M, Terasawa K, Ishioka S, Takashima S, Kudo R. Multiple primary malignancies in patients with gynecologic cancer. International Journal of Gynecological Cancer. 1995 Jan;5(1):34-9.
  4. Padala SA, Barsouk A, Thandra KC, Saginala K, Mohammed A, Vakiti A, Rawla P, Barsouk A. Epidemiology of renal cell carcinoma. World journal of oncology. 2020 Jun;11(3):79.
  5. Warren S. Multiple primary malignant tumors. A survey of the literature and a statistical study. Am J cancer. 1932;16:1358-414.
  6. Frödin JE, Ericsson J, Barlow L. Multiple primary malignant tumors in a national cancer registry: reliability of reporting. Acta oncologica. 1997 Jan 1;36(5):465-9.
  7. Wong C, Plante M, Eltabbakh G. Synchronous renal cell carcinoma and gynecologic malignancies. Gynecologic oncology. 2003 Jan 1;88(1):66-8.
  8. RABBANI F, GRIMALDI G, RUSSO P. Multiple primary malignancies in renal cell carcinoma. The Journal of urology. 1998 Oct 1;160(4):1255-9.
  9. Shaukat F, Mansha MA, Ali N, Khan AM, Abbasi AN. Incidental renal cell carcinoma in pelvic malignancies. Cureus. 2019 Jan;11(1).
  10. Sharma M, Hussain A, Sharma M. Synchronous Renal Cell Carcinoma with Carcinoma Cervix: An Unusual Clinical Presentation. Journal of South Asian Federation of Menopause Societies. 2020;8(1).

Background In India, renal cell carcinoma (RCC) is the most frequent kidney cancer with an increasing tendency, whereas cervical cancer is the second most common disease among women. Synchronicity of RCC with other malignancies is not uncommon, but with the cervical cancer is rare.  Case description A 64-year-old, postmenopausal female, presented with complaint of bleeding per vagina and was diagnosed with carcinoma cervix and later on metastatic work-up also diagnosed with right RCC. After multidisciplinary discussion, patient planned for management for cervix then followed by renal lesion. Patient received radical external beam radiotherapy followed by brachytherapy for carcinoma cervix and underwent nephrectomy for right RCC.  Conclusion Synchronous cases of cervical cancer and renal cell carcinoma are very rare. Advancement in diagnostic protocol makes these kind of cases common and multidisciplinary team decisions are required for their management.

Keywords : Carcinoma Cervix, Multidisciplinary, Renal Cell Carcinoma (RCC), Synchronous.

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