Synchronous Squamous Cell Carcinoma of the Lip and Nasopharyngeal Carcinoma – A Rare Case Report.


Authors : M. Guezar; S. Khalf; K. Oulabbes; S. Badja; D. Kamal; F.Z. Farhane; Z. Alami; T. Bouhafa; MN. El Alami Elamine; K. Hassouni

Volume/Issue : Volume 6 - 2021, Issue 4 - April

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/3gwD1LK

Abstract : The multiple primary head and neck cancers are becoming more frequent and are the cause of many diagnostic and therapeutic difficulties . Synchronous Nasopharyngeal carcinoma (NPC) and squamous cell carcinoma of the lip (SCCL) is a rare case presentation to be reported in literature. We report a rare case of synchronous presentation of NPC and SCC of the lip in a 44-years-old male patient with a history of ultraviolet radiation exposure , a poor oral hygiene and poor dietary habits. The patient first presented with a diagnosis of squamous cell carcinoma of the lower lip, the radiological assessment revealed a thickening of the posterior wall of the cavum corresponding of a nasopharyngeal carcinoma that was confirmed by biopsy with histopathological examination. The management consisted of surgical excision of the lip tumor with reconstruction of substance loss and adjuvant external radiotherapy to the tumor bed with concomitant chemoradiotherapy for nasopharyngeal carcinoma with a follow up of 24 months, without local relapse or remote metastases.

Keywords : Synchronous Carcinoma, Head and Neck Multiple Cancers, Epstein Barr Virus, Field Cancerization.

The multiple primary head and neck cancers are becoming more frequent and are the cause of many diagnostic and therapeutic difficulties . Synchronous Nasopharyngeal carcinoma (NPC) and squamous cell carcinoma of the lip (SCCL) is a rare case presentation to be reported in literature. We report a rare case of synchronous presentation of NPC and SCC of the lip in a 44-years-old male patient with a history of ultraviolet radiation exposure , a poor oral hygiene and poor dietary habits. The patient first presented with a diagnosis of squamous cell carcinoma of the lower lip, the radiological assessment revealed a thickening of the posterior wall of the cavum corresponding of a nasopharyngeal carcinoma that was confirmed by biopsy with histopathological examination. The management consisted of surgical excision of the lip tumor with reconstruction of substance loss and adjuvant external radiotherapy to the tumor bed with concomitant chemoradiotherapy for nasopharyngeal carcinoma with a follow up of 24 months, without local relapse or remote metastases.

Keywords : Synchronous Carcinoma, Head and Neck Multiple Cancers, Epstein Barr Virus, Field Cancerization.

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