Authors : Dr. P Kishore Kumar; Thokala Ruchitha; Pasumala Varun; Chinta Rohit Kumar; Dr. T Rama Rao

Volume/Issue : Volume 10 - 2025, Issue 6 - June

Google Scholar : https://tinyurl.com/3sdyx3zu

DOI : https://doi.org/10.38124/ijisrt/25jun1084

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : A rare chronic granulomatous vasculitis, Takayasu arteritis (TA) mainly affects big arteries including the aorta and its major branches. Although autoimmune pathways are strongly implicated, the precise etiology of this condition, which is most commonly observed in young Asian women, is yet unknown. The illness develops gradually, starting with vague constitutional symptoms and ending with vascular problems like ischemia, aneurysms, hypertension, and pulselessness. Clinical examination, laboratory indicators of inflammation, and sophisticated imaging methods like CT angiography and MRI are all part of the diagnostic evaluation process. Corticosteroids, immunosuppressive medications, and biologics are commonly used in treatment; in more severe cases, revascularization may be required. Early identification and specialized multidisciplinary management are crucial because of its systemic nature and its consequences. With an emphasis on recent developments and treatment concerns, this review offers an updated synopsis of Takayasu arteritis's categorization, pathogenesis, clinical characteristics, diagnostic standards, and therapy approaches.

Keywords : Takayasu Arteritis, Large-Vessel Vasculitis, Aortic Inflammation, Pulseless Disease, Angiographic Classification, Autoimmune Vasculitis, Corticosteroids, Biologic Therapy, Vascular Stenosis, Imaging in Vasculitis.

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