Authors :
Nitesh Shrestha; Hou Zhongjun
Volume/Issue :
Volume 7 - 2022, Issue 7 - July
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3QkIPXD
DOI :
https://doi.org/10.5281/zenodo.6956250
Abstract :
The morphology and volume of the brain in
TLE patients, especially hippocampus, amygdala, were
displayed by cMRI scan, EEG and post-processing of 3D
T1WI.
Methods: A total of 69 epileptic patients aged 18-60 years
were collected for re-evaluation, including EEG, routine
cMRI scan and 3D T1WI scan of the whole brain on 1.5T
and 3.0T MRI. The 3D T1WI was further post-processed
by VBM.
Results: In 1.5T MRI group, 30% were MRI negative. 20%
showed the reduction of left hippocampal volume, 10%
showed the reduction of right hippocampus, and 10%
showed reduction of left amygdala, and consistent with the
location of EEG. The right hippocampus showed a
difference in the volume of patients with control group. In
3.0T MRI group, only 10% had TLE. In 3 cases of TLE,
the volume of bilateral hippocampus in 33.33% patients
was smaller than control and consistent with the location
of EEG.
Conclusion: VBM combined with EEG and cMRI can
provide detailed information for epileptics and helps in
analysis of ROI structure, accurately measures and
calculate the volumes.
Keywords :
Epilepsy, Temporal Lobe Epilepsy (TLE), Conventional MRI (cMRI), Electroencephalography (EEG), Voxel Based Morphometry (VBM), Postprocessing, Region of interest (ROI)
The morphology and volume of the brain in
TLE patients, especially hippocampus, amygdala, were
displayed by cMRI scan, EEG and post-processing of 3D
T1WI.
Methods: A total of 69 epileptic patients aged 18-60 years
were collected for re-evaluation, including EEG, routine
cMRI scan and 3D T1WI scan of the whole brain on 1.5T
and 3.0T MRI. The 3D T1WI was further post-processed
by VBM.
Results: In 1.5T MRI group, 30% were MRI negative. 20%
showed the reduction of left hippocampal volume, 10%
showed the reduction of right hippocampus, and 10%
showed reduction of left amygdala, and consistent with the
location of EEG. The right hippocampus showed a
difference in the volume of patients with control group. In
3.0T MRI group, only 10% had TLE. In 3 cases of TLE,
the volume of bilateral hippocampus in 33.33% patients
was smaller than control and consistent with the location
of EEG.
Conclusion: VBM combined with EEG and cMRI can
provide detailed information for epileptics and helps in
analysis of ROI structure, accurately measures and
calculate the volumes.
Keywords :
Epilepsy, Temporal Lobe Epilepsy (TLE), Conventional MRI (cMRI), Electroencephalography (EEG), Voxel Based Morphometry (VBM), Postprocessing, Region of interest (ROI)
