The Covid-19 pandemic has become a frightening disease due to its easy and fast transmission. One way to deal with the spread of Covid 19 is by applying isolation to the sufferer according to the symptoms that appear. Isolation in hospitals can have physical and psychological impacts on both sufferers and their families.The aims of study were to analyze the factors of age, gender, education level, income and family with coping with stress. Family of patients treated in hospital isolation rooms. Methods: This type of research uses analytic observational with cross sectional design, using total sampling. Data collection uses a questionnaire ways of coping. The statistical test used is cross tabulation test and ordinal regression, the sample in this study was 124 respondents from families of patients who were treated at the hospital. isolation room in a regional hospital in Jember. Results: The results showed that the respondents had a fairly good coping response to the stress they experienced. There was an effect of age (0.025<0.05), education (0.00<0.05) and income (0.021<0, 05) while gender and the relationship with the patient have no effect with a value of = 0.05. Conclusion: There was an effect between factors of age, education and income, on coping with family stress of patients who are treated in the isolation room of the Regional Hospital.

Keywords : Coping, Covid-19, Isolation