The Effect of Antenatal Magnesium Sulphate for Fetal Neuroprotection in Threatened Preterm Labour: A Prospective Cohort Study


Authors : DR. RAKHI. J. MOHAN; DR.LAKSHMY.S; Dr.FIJI MD

Volume/Issue : Volume 8 - 2023, Issue 9 - September

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/rsh9ch34

DOI : https://doi.org/10.5281/zenodo.8378495

Abstract : Due to the advances in perinatal care, the survival rate of premature babies is also increasing. This lead to the increase in the learning disabilities, medical disabilities, behavioral and psychological problems among these surviving premature babies. The risk of neurological impairments such as cerebral palsy, blindness, deafness, and cognitive dysfunction are high in preterm babies. Magnesium sulphate used as the seizure prophylaxis in severe pre-eclamptic women and as a tocolytic found to have neuroprotective action in the preterm babies. Several studies concluded that exposure to both antenatal corticosteroids and magnesium sulphate was associated with lower rates of severe neurodevelopmental impairment or mortality.To determine the role of magnesium sulphate given for fetal neuro protection to women at risk of preterm birth in preventing neonatal mortality and neuro developmental morbidity.

Keywords : Preterm labour, Magnesium sulphate, Fetal neuroprotection.

Due to the advances in perinatal care, the survival rate of premature babies is also increasing. This lead to the increase in the learning disabilities, medical disabilities, behavioral and psychological problems among these surviving premature babies. The risk of neurological impairments such as cerebral palsy, blindness, deafness, and cognitive dysfunction are high in preterm babies. Magnesium sulphate used as the seizure prophylaxis in severe pre-eclamptic women and as a tocolytic found to have neuroprotective action in the preterm babies. Several studies concluded that exposure to both antenatal corticosteroids and magnesium sulphate was associated with lower rates of severe neurodevelopmental impairment or mortality.To determine the role of magnesium sulphate given for fetal neuro protection to women at risk of preterm birth in preventing neonatal mortality and neuro developmental morbidity.

Keywords : Preterm labour, Magnesium sulphate, Fetal neuroprotection.

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