Due to the advances in perinatal
care, the survival rate of premature babies is also increasing. This lead to the increase in the learning
disabilities, medical disabilities, behavioral and psychological problems among these surviving
premature babies. The risk of neurological impairments such as cerebral palsy, blindness, deafness, and
cognitive dysfunction are high in preterm babies. Magnesium sulphate used as the seizure prophylaxis
in severe pre-eclamptic women and as a tocolytic found to have neuroprotective action in the preterm
babies. Several studies concluded that exposure to both antenatal corticosteroids and magnesium
sulphate was associated with lower rates of severe neurodevelopmental impairment or mortality.To determine the role of magnesium sulphate given for fetal neuro protection to women at
risk of preterm birth in preventing neonatal mortality and neuro developmental morbidity.
Keywords : Preterm labour, Magnesium sulphate, Fetal neuroprotection.