The Effectiveness of Sucrose as a Pain Reducing Substance during Procedures in NICU


Authors : Dr. Venugopal Reddy. I; Dr. Veera Loknadha Reddy. M

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/3VvzOP8

DOI : https://doi.org/10.5281/zenodo.7896368

Abstract : The medical community has long been aware of infant distress, which typically happens in a hospital context. It has become clear that many newborns admitted to the neonatal critical care unit are not receiving enough therapy for stress and discomfort because both premature and full-term infants experience pain. The use of enhanced management techniques to decrease stress and pain whenever possible and to offer fast and effective treatment when suffering cannot be avoided is supported by both scientific and humanitarian reasons. At Kasturba Hospital in Manipal, Karnataka, between October 2012 and September 2013, parents of 128 term newborns who had been evaluated for eligibility took part in the study after giving their informed consent. The infants were all congenitally healthy and free of abnormalities. According to this study, 24% sucrose performs better than 10% dextrose as an analgesic for procedural pain in term neonates. The physiological parameters of all 128 neonates were recorded, including heart rate, oxygen saturation, total cry time, and pain evaluation using the NIPS score. Only 78 newborns' salivary cortisol levels were investigated. The following criteria revealed no discernible differences between the 24% sucrose and 10% dextrose in terms of reducing babies' procedural pain. The median total cry duration for both operations was shorter in the 24% sucrose group than in the 10% dextrose group. For heel lancing, 24% sucrose significantly decreased discomfort in 37.5% of infants at 1 minute, 87.5% of neonates at 3 minutes, and 22.5 seconds vs. 130 seconds for venipuncture, compared to 10% dextrose. This implies that 24% sucrose, as opposed to 10% dextrose, works better as an analgesic for procedural pain in term babies.

Keywords : New Borns, Salivary Cortisol, Sucrose, Dextrose, Pain.

The medical community has long been aware of infant distress, which typically happens in a hospital context. It has become clear that many newborns admitted to the neonatal critical care unit are not receiving enough therapy for stress and discomfort because both premature and full-term infants experience pain. The use of enhanced management techniques to decrease stress and pain whenever possible and to offer fast and effective treatment when suffering cannot be avoided is supported by both scientific and humanitarian reasons. At Kasturba Hospital in Manipal, Karnataka, between October 2012 and September 2013, parents of 128 term newborns who had been evaluated for eligibility took part in the study after giving their informed consent. The infants were all congenitally healthy and free of abnormalities. According to this study, 24% sucrose performs better than 10% dextrose as an analgesic for procedural pain in term neonates. The physiological parameters of all 128 neonates were recorded, including heart rate, oxygen saturation, total cry time, and pain evaluation using the NIPS score. Only 78 newborns' salivary cortisol levels were investigated. The following criteria revealed no discernible differences between the 24% sucrose and 10% dextrose in terms of reducing babies' procedural pain. The median total cry duration for both operations was shorter in the 24% sucrose group than in the 10% dextrose group. For heel lancing, 24% sucrose significantly decreased discomfort in 37.5% of infants at 1 minute, 87.5% of neonates at 3 minutes, and 22.5 seconds vs. 130 seconds for venipuncture, compared to 10% dextrose. This implies that 24% sucrose, as opposed to 10% dextrose, works better as an analgesic for procedural pain in term babies.

Keywords : New Borns, Salivary Cortisol, Sucrose, Dextrose, Pain.

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