One of the sub-sectors in manufacturing companies, namely the pharmaceutical subsector have current assets that are greater than fixed assets. Based on data from balance sheet of companies, it is known that there are 8 out of 10 companies that have more current assets compared to fixed assets. The purpose of this study is to determine the effect of asset structure and working capital management on company profitability. The data analysis method in this research is the dependent method. The variables in this study are asset structure, inventory turnover, accounts receivable turnover, and company profitability. The results of the study are based on the results of the t statistical test (partial test) that only variable inventory turnover has no effect on profitability, the rest of the other variables are asset structure and receivables turnover have negative effect on profitability as measured by the GPM ratio. Based on the F statistical test (simultaneous test), the asset structure, inventory turnover, and accounts receivable turnover together or simultaneously have a significant effect on profitability.

Keywords : Asset Structure, Working Capital Management, Profitability