The Influence of Political Homophily on Pro-Vaccination Attitudes and Vaccine Hesitancy: A Case Study of TikTok


Authors : Salome Mbah

Volume/Issue : Volume 10 - 2025, Issue 1 - January


Google Scholar : https://tinyurl.com/5ykv8234

Scribd : https://tinyurl.com/bdf2a7ms

DOI : https://doi.org/10.5281/zenodo.14759716


Abstract : Political homophily, the tendency of individuals to connect with others who share similar political ideologies, plays a significant role in shaping attitudes and behaviors in digital spaces. This study investigates the influence of political homophily on pro-vaccination attitudes and vaccine hesitancy within the TikTok platform, which has emerged as a dominant medium for public health communication. Employing a quantitative research approach, including a factorial 3x3 experimental design, the study explores the extent to which politically aligned messaging on TikTok affects user engagement with vaccination-related content. Findings reveal that while political homophily enhances the acceptance of pro-vaccination messages among like-minded groups, it simultaneously exacerbates vaccine hesitancy in politically polarized audiences. Contrary to the assumption that political ideology alone determines vaccine attitudes, the study highlights the complex interplay of social, cultural, and emotional factors facilitated by TikTok’s interactive and algorithm-driven ecosystem. The research underscores the platform's potential as a double-edged sword in health communication: a space for both fostering inclusive, positive health messaging and amplifying polarized perspectives. This study contributes to the growing body of knowledge on the intersection of social media, political homophily, and public health behavior. It offers actionable insights for public health practitioners, policymakers, and communication strategists aiming to design effective campaigns to counter vaccine hesitancy. By leveraging TikTok's unique engagement mechanisms and addressing underlying emotional and political biases, stakeholders can better navigate the challenges of vaccine communication in a politically diverse digital landscape. The implications extend beyond TikTok, offering a framework for utilizing social media as a tool for advancing global health initiatives.

Keywords : Political Homophily, Pro-Vaccination Attitudes, Vaccine Hesitancy, TikTok, Public Health Communication.

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Political homophily, the tendency of individuals to connect with others who share similar political ideologies, plays a significant role in shaping attitudes and behaviors in digital spaces. This study investigates the influence of political homophily on pro-vaccination attitudes and vaccine hesitancy within the TikTok platform, which has emerged as a dominant medium for public health communication. Employing a quantitative research approach, including a factorial 3x3 experimental design, the study explores the extent to which politically aligned messaging on TikTok affects user engagement with vaccination-related content. Findings reveal that while political homophily enhances the acceptance of pro-vaccination messages among like-minded groups, it simultaneously exacerbates vaccine hesitancy in politically polarized audiences. Contrary to the assumption that political ideology alone determines vaccine attitudes, the study highlights the complex interplay of social, cultural, and emotional factors facilitated by TikTok’s interactive and algorithm-driven ecosystem. The research underscores the platform's potential as a double-edged sword in health communication: a space for both fostering inclusive, positive health messaging and amplifying polarized perspectives. This study contributes to the growing body of knowledge on the intersection of social media, political homophily, and public health behavior. It offers actionable insights for public health practitioners, policymakers, and communication strategists aiming to design effective campaigns to counter vaccine hesitancy. By leveraging TikTok's unique engagement mechanisms and addressing underlying emotional and political biases, stakeholders can better navigate the challenges of vaccine communication in a politically diverse digital landscape. The implications extend beyond TikTok, offering a framework for utilizing social media as a tool for advancing global health initiatives.

Keywords : Political Homophily, Pro-Vaccination Attitudes, Vaccine Hesitancy, TikTok, Public Health Communication.

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