Authors : Kuchekar S. D; Dr. Panaskar A.N; Dr.Panaskar B. A; Bhosale R.D; Jadhav R.M; Valkunde R.M; Dupade R.D.; Pinjari E.E.

Volume/Issue : Volume 9 - 2024, Issue 6 - June

Google Scholar : https://tinyurl.com/47amzm29

Scribd : https://tinyurl.com/2acrv45y

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUN349

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Abstract : Ficus hispida (FH) Linn is a year-round moderate-sized tree that is grown in the wild or under cultivation for its tasty fruits and cultural significance. It can be found all over India's subtropical regions. The purpose of this study was to assess the ficus hispida leaf methanolic extract's in vitro purgative efficacy on chicken ileum. Anti-inflammatory, anti-emetic, anti- ulcer, cardioprotective, wound-healing, antifungal, antimicrobial, purgative, anti-diarrheal, and spasmodic properties are among the uses for this plant. Numerous phytochemical categories, including alkaloids, carbohydrates, proteins, amino acids, phenols, flavonoids, glycosides, fat, and fixed oil, are among the many different types of bioactives found in Ficus hispida. Additionally, a phytochemical investigation was done to determine which active ingredients possessed purgative properties. Constipation is treated with laxatives to encourage the emptying of faces. Saline purgatives are salts with strongly charged ions that stay inside the bowel's lumen or route because they are unable to move through biological membranes with ease. Sodium sulphate, magnesium hydroxide, and magnesium sulphate are a few salts that are frequently utilised.  The fluid moves from the lumen into circulation through the process of osmosis in a hypotonic solution, which causes the tissue to shrink.  Hypertonic solution, which causes tissue swelling by transferring fluid from the cell into the lumen.  In cases where there was no fluid movement across the intestinal barrier when using an isotonic solution.

Keywords : Purgative Activity, Ficus hispida, Methanolic Extract.

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