Authors :
Akinremi-Aina Titilope; Dangana Jonathan
Volume/Issue :
Volume 9 - 2024, Issue 9 - September
Google Scholar :
https://tinyurl.com/24ty26wb
Scribd :
https://tinyurl.com/529t68vw
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24SEP576
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Background:
Tuberculosis (TB) has continued to be a major
health concern to man and has affected majority of the
population around the world. In the World Health
Organisation (WHO)’s estimate, Nigeria is second in
Africa and seventh in the world with regard to cases.
Since Lagos is the most populous state in Nigeria, it has
made a high number of tuberculosis cases. Since there is
no cure for TB without taking the prescription drugs,
noncompliance has been as frequent as the disease,
leading to treatment failure, drug resistant TB and
increased cost of healthcare. The e-refill prescription
system which is an electronic prescription refill system is
targeted to increase medical compliance amongst TB
patients consequently improving overall health.
Aim:
The purpose of this study is therefore to evaluate the
factors which determine medication compliance among
TB patients on the e-refill prescription in health facilities
in Lagos state.
Setting:
Various healthcare facilities across Lagos.
Methodology:
This study employed the cross-sectional method. For
sampling, we opted for a purposive sampling approach to
select the patients. The sample size, determined using the
Kish formula, comprised approximately 338 TB patients.
In order to collect data on critical factors such as patient’s
satisfaction, factors influencing e-refill medication
adherence, and the willingness to adopt the e-refill system,
this study made use of in-depth interview and semi-
structured question. Furthermore, the collected data was
analysed with SPSS software, with two team members
independently coding the interview transcripts to identify
emerging themes and resolve discrepancies through
consensus discussions.
Results:
A large proportion of the participants fell between
the ages of 28 to 38 years (45.9%), (53.0%) were married,
and the Yoruba ethnic group dominated the population at
(49.4%). Most patients received care from government-
owned facilities (75.1%). 68.6% considered medical
adherence important. Of factors influencing medical
adherence, (47%) said that forgetfulness often affected
their adherence, and (23.7%) cited the side effect. Of
those surveyed, 54.4% expressed interest in using the e-
Refill system, and 60.7% were knowledgeable about it.
Ease of use (32.8%) and system trust (29.9%) are the
main variables influencing readiness to utilise the e-Refill
system.
Conclusion:
The e-Refill system has shown potential for success
in improving medication adherence among TB patients in
Lagos state. However, it is important to address
challenges such as limited access to healthcare and
reluctance among certain patient groups need to be
addressed. To get maximum result possible from the
system, it is important to take steps to enhance patient
engagement, address stigma associated with the illness,
and ensure sustained support over the duration of the
treatment.
Contribution:
The study highlights the significance of niche
interventions geared towards promoting medication
adherence and improving TB treatment outcomes in
resource-constrained environments.
Keywords :
Tuberculosis, e-Refill Prescription System, Medication Adherence.
References :
- Gopalaswamy R, Dusthackeer VNA, Kannayan S, Subbian S. Extrapulmonary Tuberculosis—An Update on the Diagnosis, Treatment and Drug Resistance. Journal of Respiration. 2021 May 26;1(2):141–64.
- World Health Organization. Global tuberculosis report 2020 [Internet]. www.who.int. 2020. Available from: https://www.who.int/publications/i/item/9789240013131
- Adepoju VA, Oladimeji KE, Adejumo OA, Adepoju OE, Adelekan A, Oladimeji O. Knowledge of International Standards for Tuberculosis Care among Private Non-NTP Providers in Lagos, Nigeria: A Cross-Sectional Study. Tropical Medicine and Infectious Disease. 2022 Aug 18;7(8):192.
- Koo HK, Min J, Kim HW, Lee J, Kim JS, Park JS, et al. Prediction of treatment failure and compliance in patients with tuberculosis. BMC Infectious Diseases [Internet]. 2020 Aug 24;20:622. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446045/
- Vernon A, Fielding K, Savic R, Dodd L, Nahid P. The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials. PLOS Medicine. 2019 Dec 10;16(12):e1002884.
- Bhargava A, Bhargava M, Juneja A. Social determinants of tuberculosis: context, framework, and the way forward to ending TB in India. Expert Review of Respiratory Medicine. 2020 Oct 20;15(7):1–17.
- Vejdani M, Varmaghani M, Meraji M, Jamali J, Hooshmand E, Vafaee-Najar A. Electronic prescription system requirements: a scoping review. BMC Medical Informatics and Decision Making. 2022 Sep 3;22(1).
- Sazali MF, Rahim SSSA, Mohammad AH, Kadir F, Payus AO, Avoi R, et al. Improving tuberculosis medication adherence: The potential of integrating digital technology and health belief model. Tuberculosis and Respiratory Diseases. 2022 Dec 23;86(2).
- Aremu TO, Oluwole OE, Adeyinka KO, Schommer JC. Medication adherence and compliance: Recipe for improving patient outcomes. Pharmacy. 2022 Aug 28;10(5).
- Mesa JM. Sampling: How to Select Participants in My Research study? Anais Brasileiros De Dermatologia [Internet]. 2016;91(3):326–30. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938277/
- Koulayev S, Simeonova E, Skipper N. Can Physicians Affect Patient Adherence With Medication? Health Economics. 2016 Jun 16;26(6):779–94.
- Schultz WM, Kelli HM, Lisko JC, Varghese T, Shen J, Sandesara P, et al. Socioeconomic Status and Cardiovascular Outcomes: Challenges and Interventions. Circulation [Internet]. 2018;137(20):2166–78. Available from: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.029652
- Shah R, Shah A, Patel P, Thakker R. Stigma associated with tuberculosis - An Indian perspective. National Journal of Physiology, Pharmacy and Pharmacology. 2020;10(7):1.
- Barik AL, Indarwati R, Sulistiawati S. The Effectiveness Of Using Text Messages Reminder On Adherence With Tuberculosis Patients: A Systematic Review. STRADA Jurnal Ilmiah Kesehatan. 2020 Nov 1;9(2):751–60.
- Mohammed Malih Radhi, Shatha Mahmood Niazy, Sameeha Naser Abed. Individual-related factors associated treatment adherence among hypertensive patients. Journal of Public Health in Africa [Internet]. 2023 May 24;14(6). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395365/
- Javed SA, Liu S, Mahmoudi A, Nawaz M. Patients’ satisfaction and public and private sectors’ health care service quality in Pakistan: Application of grey decision analysis approaches. The International Journal of Health Planning and Management. 2018 Aug 30;34(1).
- Pedersen CA, Schneider PJ, Scheckelhoff DJ. ASHP national survey of pharmacy practice in hospital settings: Dispensing and administration—2014. American Journal of Health-System Pharmacy. 2015 Jul 1;72(13):1119–37.
- Nigussie S, Edessa D. The Extent and Reasons for Dissatisfaction From Outpatients Provided With Pharmacy Services at Two Public Hospitals in Eastern Ethiopia. Frontiers in Pharmacology [Internet]. 2018 Oct 12;9. Available from: https://www.frontiersin.org/articles/10.3389/fphar.2018.01132/full
- Gulumbe BH, Adesola RO. Revisiting the blind spot of substandard and fake drugs as drivers of antimicrobial resistance in LMICs. Annals of Medicine & Surgery. 2023 Feb;85(2):122–3.
- Taylor K, Singer S, May M, Gülsemin Durdu, Petermann‐Meyer A. Outcome comparison of integrated psycho‐oncological care versus unstructured care—Results of a non‐randomised open‐label two‐arm trial. European journal of cancer care. 2019 Jun 27;28(5).
- Ionescu SV. E-prescription using blockchain technology [Internet]. IEEE Xplore. 2022 [cited 2023 Feb 10]. p. 1–7. Available from: https://ieeexplore.ieee.org/document/10034520
- Hossain N, Yokota F, Sultana N, Ahmed A. Factors Influencing Rural End-Users’ Acceptance of e-Health in Developing Countries: A Study on Portable Health Clinic in Bangladesh. Telemedicine and e-Health. 2019 Mar;25(3):221–9.
- Annisa AT, Yasin NM, Kristina SA. THE ROLE OF THE E-PRESCRIBING SYSTEM IN HEALTHCARE: A SYSTEMATIC REVIEW. Jurnal Farmasi Sains dan Praktis [Internet]. 2023 Mar 25;9(1):40–8. Available from: http://journal.unimma.ac.id/index.php/pharmacy/article/view/8257
- Shadadeh F, Samadbeik M, Amiri F, Hajipourtalebi A. The Digital Gap in Patients’ Use of Health Information Technology and Effective Factors and Strategies; a Systematic Review. Health Research Journal. 2019 Jul 1;4(3):181–8.
- Sahi MA, Abbas H, Saleem K, Yang X, Derhab A, Orgun MA, et al. Privacy Preservation in e-Healthcare Environments: State of the Art and Future Directions. IEEE Access. 2018;6:464–78.
Background:
Tuberculosis (TB) has continued to be a major
health concern to man and has affected majority of the
population around the world. In the World Health
Organisation (WHO)’s estimate, Nigeria is second in
Africa and seventh in the world with regard to cases.
Since Lagos is the most populous state in Nigeria, it has
made a high number of tuberculosis cases. Since there is
no cure for TB without taking the prescription drugs,
noncompliance has been as frequent as the disease,
leading to treatment failure, drug resistant TB and
increased cost of healthcare. The e-refill prescription
system which is an electronic prescription refill system is
targeted to increase medical compliance amongst TB
patients consequently improving overall health.
Aim:
The purpose of this study is therefore to evaluate the
factors which determine medication compliance among
TB patients on the e-refill prescription in health facilities
in Lagos state.
Setting:
Various healthcare facilities across Lagos.
Methodology:
This study employed the cross-sectional method. For
sampling, we opted for a purposive sampling approach to
select the patients. The sample size, determined using the
Kish formula, comprised approximately 338 TB patients.
In order to collect data on critical factors such as patient’s
satisfaction, factors influencing e-refill medication
adherence, and the willingness to adopt the e-refill system,
this study made use of in-depth interview and semi-
structured question. Furthermore, the collected data was
analysed with SPSS software, with two team members
independently coding the interview transcripts to identify
emerging themes and resolve discrepancies through
consensus discussions.
Results:
A large proportion of the participants fell between
the ages of 28 to 38 years (45.9%), (53.0%) were married,
and the Yoruba ethnic group dominated the population at
(49.4%). Most patients received care from government-
owned facilities (75.1%). 68.6% considered medical
adherence important. Of factors influencing medical
adherence, (47%) said that forgetfulness often affected
their adherence, and (23.7%) cited the side effect. Of
those surveyed, 54.4% expressed interest in using the e-
Refill system, and 60.7% were knowledgeable about it.
Ease of use (32.8%) and system trust (29.9%) are the
main variables influencing readiness to utilise the e-Refill
system.
Conclusion:
The e-Refill system has shown potential for success
in improving medication adherence among TB patients in
Lagos state. However, it is important to address
challenges such as limited access to healthcare and
reluctance among certain patient groups need to be
addressed. To get maximum result possible from the
system, it is important to take steps to enhance patient
engagement, address stigma associated with the illness,
and ensure sustained support over the duration of the
treatment.
Contribution:
The study highlights the significance of niche
interventions geared towards promoting medication
adherence and improving TB treatment outcomes in
resource-constrained environments.
Keywords :
Tuberculosis, e-Refill Prescription System, Medication Adherence.