The Relationship between Fragmented QRS and Coronary Arterial Lesion Severity in Patients with Acute Coronary Syndrome Inhaji Adam Malik General Hospital, Medan, Indonesia


Authors : Mega Almira; Refli Hasan; Yuke Sarastri; Harris Hasan; Anggia Chairuddin Lubis; Teuku Bob Haykal

Volume/Issue : Volume 7 - 2022, Issue 1 - January

Google Scholar : http://bitly.ws/gu88

Scribd : https://bit.ly/3KCsBXC

DOI : https://doi.org/10.5281/zenodo.5894219

: Almost half of the causes of cardiovascular death are the result of Acute Myocardial Infarction (AMI). Acute coronary syndrome (ACS) consisting of unstable angina pectoris (APTS), non-ST elevation acute myocardial infarction (IMANEST) and ST elevation acute myocardial infarction (AMIEST) was the leading cause of death in adults and accounted for 16.7% of deaths from all groups. age. The SYNTAX score is a score system that is comprehensively formulated to describe the complexity of coronary artery lesions based on angiographic results and predict the final outcome of percutaneous coronary intervention (IKAP) or coronary artery bypass grafting.(CABG). QRS (fQRS) fragmentation on the ECG is associated with the presence of myocardial scarring, ischemia, and fibrosis stemming from defects in signal transduction processes and ventricular depolarization. Objective: The purpose of this study was to determine the relationship between QRS fragmentation and the severity of coronary artery lesions as assessed by the SYNTAX score in patients with acute coronary syndromes. Methods: The study involved acute coronary syndrome patients who underwent coronary angiography at the Haji Adam Malik General Hospital in Medan in the period January 2020 to October 2020. All subjects underwent ECG examination and SYNTAX score assessment. Statistical analysis was performed to assess QRS fragmentation with the severity of coronary artery lesions. Results: 27 subjects with QRS fragmentation experienced moderate-severe lesion severity as many as 25 people (46.3%) and only 2 people with low lesion severity (3.7%), while 22 subjects without QRS fragmentation had lesion severity. low coronary arteries and only 5 people (9.3%) had moderate-severe lesions. Based on the analysis, there was a statistically significant relationship between QRS fragmentation images and the severity of coronary artery lesions in patients with acute coronary syndromes with p value < 0.001. Patients with QRS fragmentation compared with non-fragmented QRS patients had a 35x risk of experiencing moderate-severe severity. A total of 27 subjects found that QRS fragmentation had a moderate strength relationship with the SYNTAX score and the direction of the correlation was positive and statistically significant. Conclusion: There is a relationship between QRS fragmentation in patients with acute coronary syndromes and the severity of coronary artery lesions as assessed by the SYNTAX score.

Keywords : acute coronary syndrome, SYNTAX score, QRS fragment fragmentation.

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