In spite of plentiful health-related quality of life (HRQoL) implements are disposable for diabetic patients, the longitude of these measurements may restrict their feasibility to habitual application. Also, these instruments do not differentiate the elements for the diabetes-generic and specific HRQoL. This study reports the reliability and validity analyses of Vietnamese Diabetes Quality of Life (VNDQOL) questionnaire on type 2 diabetic patients in Tam Binh district health center, Vinh Long province, Vietnam. Methods: An initial supply of the elements has been germinated place on a literature review. Both English and Vietnamese versions were inspected by five experts, then a try out was carried on 45 type 2 diabetic patients from 35 to 65 years old to validate the VNDQOL questionnaire. The IBM SPSS 22.0 software was used the statistical analysis. The Cronbach’s alpha has been used the reliability evaluation. Results: After the review of the generic and specific QoL measures, a new questionnaire was developed that was VNDQOL.

Keywords : Diabetes Mellitus, VNDQOL, HRQoL, Vietnamese.