The Revolution of Genomics Technologies and their Applications in Basic and Clinical Science


Authors : Michael Halim

Volume/Issue : Volume 7 - 2022, Issue 3 - March

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3jocsbX

DOI : https://doi.org/10.5281/zenodo.6433758

The Human Genome Project focuses on identifying and mapping human genome genes and the base pair of DNA. Bioinformatics is an emerging field that plays a significant role in exploiting the existing amount of genome data to solve a wide range of genomic problems. The emergence and implementation of bioinformatics are vital in providing a platform for managing, analysing, and implementing the existing data on genomics. One of the leading benefits of bioinformatics is the increased capacity to perform system-wide analysis involving genomes, phonemes, and explanations on the association between phenotypes and genotypes. Modern technologies and revolutions in genomics impact a wide range of areas and are beneficial in resolving diverse problems in these fields, including environmental impacts, low-profit margins, and diseases. The revolution significantly influences thirdgeneration sequencing to overcome second-generation sequencing weaknesses in various genome regions. Genomics' future is unpredictable and is anticipated to accelerate faster, accompanied by security, privacy, and human genomic challenges. Based on the previous impacts, genomics will continue to have immeasurable effects on different fields, the environment, biology, and society. The concepts of epigenomics, functional genomics, and metagenomics reveal the benefits of genomics – a broad area relevant and significant in the current era. Genomic concepts can be used to solve a wide range of challenges, especially concerning thirdgeneration sequencing. In the current era, genomics is not only beneficial. Modern technology has also significantly revolutionised to enhance the implementation in solving problems with genes and proteins and their interactions.

Keywords : Genomics," "human genome," "bioinformatics," "genomic problems," "emergence and implementation of bioinformatics," "revolution of genomic," "genomic concepts," "third-generation sequencing," "genomic practice."

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