COVID-19, severe acute respiratory syndrome (SARS-CoV-2) being causative agent of the major outbreak of respiratory infection with a very low mortality rate. In this review article, we discuss here the basic virus of SARS- CoV-2, including the genome and its proximal origin, the specific mutations, the global variants, its adverse epidemiology, various therapies and immunization against the SARS-CoV-2

Keywords : SARS-CoV-2, GLOBAL VARIANTS OF CORONAVIRUS, EPIDEMIOLOGY, IMMUNIZATION, MUTATIONS, VARIANTS, VACCINE, MONOCLONAL ANTIBODIES, SARS, MERS.