Authors : Aqeel Ahmad Khan; Suboohi Irshad; Shaista Parveen S.; Javed Ahamd Khan; Shabir Ahmad Parray; Shagufta Nikhat

Volume/Issue : Volume 10 - 2025, Issue 8 - August

Google Scholar : https://tinyurl.com/j92xfjv7

Scribd : https://tinyurl.com/ya3pa4tr

DOI : https://doi.org/10.38124/ijisrt/25aug223

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Abstract : A randomized, single-blind, standard-controlled clinical trial was conducted to assess the therapeutic efficacy of Anjeer (Ficus carica) in the management of Type 2 Diabetes Mellitus (T2DM), traditionally referred to as Ziabetus Shakri. Sixty confirmed T2DM patients were randomly assigned into two groups: Group A (Test) and Group B (Control), with 30 participants in each. Group A received the investigational drug (Ficus carica) at a dosage of 3 grams twice daily, while Group B was administered Metformin 500 mg (Cipla), one tablet twice daily, over a period of 45 days. The findings demonstrated that the test formulation significantly improved certain subjective symptoms, including fatigue (p<0.001) and unexplained weight loss (p<0.01). However, no statistically significant changes were observed in polyuria, polydipsia, polyphagia, or progressive weakness (p>0.05). Regarding objective parameters, Group A exhibited notable improvements in fasting blood sugar (FBS), postprandial blood sugar (PPBS), urine glucose levels (p<0.01), and glycated hemoglobin (HbA1c) (p<0.05). In contrast, the control group did not show statistically significant changes in FBS and urine glucose (p>0.05). These results suggest that Ficus carica may offer potential as an adjunctive treatment for T2DM, particularly in alleviating specific clinical symptoms and improving glycemic control.

Keywords : Ziabetus Shakari, Diabetic Mellitus, Anjeer, Metformin, HbA1c.

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