Time-Dependent Study of Blood Flow Through Vertebral Artery Analysing the Effect of Stenosis


Authors : Josephina Harris; Ajit Paul; Bhavna Singh Ghosh

Volume/Issue : Volume 10 - 2025, Issue 7 - July


Google Scholar : https://tinyurl.com/2x7vmeee

Scribd : https://tinyurl.com/yc4f3wy6

DOI : https://doi.org/10.38124/ijisrt/25jul1204

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Abstract : Vertebral artery stenosis (VAS) is a major contributor to ischemic strokes in the posterior circulation. Computational fluid dynamics (CFD) has emerged as a valuable tool in simulating blood flow dynamics in both healthy and pathologically altered vessels. This study explores the temporal characteristics of blood flow in the vertebral arteries using numerical simulations. We model blood flow under pulsatile conditions in anatomically realistic healthy and stenosed vertebral arteries and evaluate velocity distributions and pressure variations, over a cardiac cycle. The study aims to enhance understanding of hemodynamic alterations caused by stenosis and their implications in vertebrobasilar insufficiency and stroke risk.

Keywords : CFD; Hemodynamics; Vertebral Artery Stenosis; Pressure.

References :

  1. Qiao, A., Dai, X., Niu, J., & Jiao, L. (2016). Hemodynamics in stented vertebral artery ostial stenosis based on computational fluid dynamics simulations. Computer methods in BiomeChaniCs and BiomediCal engineering19(11), 1190-1200.
  2. Hassan, T., Ezura, M., Timofeev, E. V., Tominaga, T., Saito, T., Takahashi, A., ... & Yoshimoto, T. (2004). Computational simulation of therapeutic parent artery occlusion to treat giant vertebrobasilar aneurysm. American journal of neuroradiology25(1), 63-68.
  3. Gamilov, T., Simakov, S., & Kopylov, P. (2018). Computational modeling of multiple stenoses in carotid and vertebral arteries. Trends in Biomathematics: Modeling, Optimization and Computational Problems: Selected Works From the BIOMAT Consortium Lectures, Moscow 2017, 301-312.
  4. Ali, R., Kaur, R., Katiyar, V. K., & Singh, M. P. (2009). Mathematical modeling of blood flow through vertebral artery with stenoses. Indian Journal of Biomechanics151, 151-158.
  5. Wake-Buck, A. K., et al. (2012). Hemodynamic characteristics of the vertebrobasilar system analyzed using MRI-based models. PLoS ONE, 7(12): e51346.
  6. Jozwik, K., & Obidowski, D. (2010). Numerical simulations of the blood flow through vertebral arteries. Journal of Biomechanics, 43(2), 177–185.
  7. Sinnott, M., Cleary, P. W., & Prakash, M. (2006). An Investigation of Pulsatile Blood Flow in a Bifurcation Artery Using a Grid-Free Method. Proc. Fifth International Conference on CFD in the Process Industries.

Vertebral artery stenosis (VAS) is a major contributor to ischemic strokes in the posterior circulation. Computational fluid dynamics (CFD) has emerged as a valuable tool in simulating blood flow dynamics in both healthy and pathologically altered vessels. This study explores the temporal characteristics of blood flow in the vertebral arteries using numerical simulations. We model blood flow under pulsatile conditions in anatomically realistic healthy and stenosed vertebral arteries and evaluate velocity distributions and pressure variations, over a cardiac cycle. The study aims to enhance understanding of hemodynamic alterations caused by stenosis and their implications in vertebrobasilar insufficiency and stroke risk.

Keywords : CFD; Hemodynamics; Vertebral Artery Stenosis; Pressure.

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Paper Submission Last Date
31 - December - 2025

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