Authors :
Gokul Ganesan, Sreela Dasgupta, Niloufer K. Kotwal.
Volume/Issue :
Volume 4 - 2019, Issue 4 - April
Google Scholar :
https://goo.gl/DF9R4u
Scribd :
https://bit.ly/2HOZXTH
Abstract :
An ultrasound assisted green synthetic protocol has been developed for synthesis of substituted benzalazines using sonicator probe in aqueous medium. Several conventional synthetic methods are known for Bis-Schiff bases, they however suffer from low yields, long reaction duration, harsh conditions & use of organic solvent medium like alcohol, DCM etc.[2] The ultrasound route offered superior yields & shorter reaction times as compared to conventional methods & went smoothly in aqueous medium as against use of organic solvents. Most of the reactions went to completion with greater than 90% yields within 1 minute as indicated by TLC.
Keywords :
Azine, Antifungal, Docking Studies, Lanosterol Demethylase.
An ultrasound assisted green synthetic protocol has been developed for synthesis of substituted benzalazines using sonicator probe in aqueous medium. Several conventional synthetic methods are known for Bis-Schiff bases, they however suffer from low yields, long reaction duration, harsh conditions & use of organic solvent medium like alcohol, DCM etc.[2] The ultrasound route offered superior yields & shorter reaction times as compared to conventional methods & went smoothly in aqueous medium as against use of organic solvents. Most of the reactions went to completion with greater than 90% yields within 1 minute as indicated by TLC.
Keywords :
Azine, Antifungal, Docking Studies, Lanosterol Demethylase.