Regional anaesthesia is used as a part of multimodal analgesic strategy for post thoracotomy pain. Several techniques have been described for providing post operative analgesia after thoracotomy which include central neuraxial block (epidural analgesia), paravertebral block. These techniques are invasive. It is challenging to perform these modalities in paediatric patients. Ultrasound guided erector spinae plane (ESP) blockis a newly described technique for managing post thoracotomy pain. A total of 3 paediatric patients belonging to ASA grade 3 received ultrasound guided unilateral ESP block. The primary objective of this study was to assess post operative analgesia in the form of time required to first dose of rescue analgesia and secondary objective was monitoring of intra operative haemodynamic parameters. The duration of post operative analgesia was 480, 420 and 480 minutes respectively of the 3 cases. The haemodynamic parameters of all 3 cases were within normal limits Ultrasound‑guided ESP block provided effective pre emptive analgesia for paediatric thoracotomy. Administration of ultrasound guided single shot erector spinae plane block in paediatric thoracotomy provides effective perioperative analgesia