Authors :
Satish Kumar B P; Dr. Nandini H B.; Dr. Medhini H Gowda
Volume/Issue :
Volume 8 - 2023, Issue 11 - November
Google Scholar :
http://tinyurl.com/mtrbyt99
Scribd :
http://tinyurl.com/5av7mjx6
DOI :
https://doi.org/10.5281/zenodo.10390797
Abstract :
Pharmacovigilance (PV), initiated by the
World Health Organisation (WHO) in 1968,
encompasses the systematic exploration and
management of adverse effects associated with
medications. The Programme for International Drug
Monitoring (PIDM) and WHO Collaborating Centre for
International Drug Monitoring (UMC) engage 134
nations, aiming to standardize PV practices amid global
pharmaceutical expansion. Adverse drug reactions
(ADRs) incur significant morbidity and financial
burdens, especially in countries like India with diverse
drug usage patterns. Adverse drug events (ADEs),
including medication errors and ADRs, challenge global
public health, causing harm and escalating healthcare
costs. Underreporting persists despite ADR Monitoring
Centres (AMCs), necessitating enhanced training, public
education, and integrated drug safety education.
This article delves into the pervasive issue of
underreporting ADEs, exploring its extent and
underlying factors. Analyzing the current state is crucial
for developing potential solutions to bolster ADE
reporting and advance patient safety. ADR identification
methods are categorized into combined, active, and
passive strategies. Combined methods integrate various
approaches comprehensively. Active methods, using
computerized reporting and medical note reviews,
exhibit reasonable detection rates. Passive methods,
specifically spontaneous reporting, reveal lower rates
due to workflow interruptions and lack of knowledge.
Underreporting factors span fear-based, knowledge-
based, system-based, and organizational-based elements.
Fear of adverse consequences fosters a culture of silence,
hindering comprehensive reporting.
Rational solutions involve establishing a global
consensus, educational interventions, improving
electronic reporting systems, and exploring alternative
data sources. Continuous efforts are imperative to
enhance knowledge, attitudes, and reporting practices,
ultimately improving medication safety and
patient care outcomes.
Keywords :
Underreporting, Healthcare Professional, Solutions, Adverse Drug Reaction.
Pharmacovigilance (PV), initiated by the
World Health Organisation (WHO) in 1968,
encompasses the systematic exploration and
management of adverse effects associated with
medications. The Programme for International Drug
Monitoring (PIDM) and WHO Collaborating Centre for
International Drug Monitoring (UMC) engage 134
nations, aiming to standardize PV practices amid global
pharmaceutical expansion. Adverse drug reactions
(ADRs) incur significant morbidity and financial
burdens, especially in countries like India with diverse
drug usage patterns. Adverse drug events (ADEs),
including medication errors and ADRs, challenge global
public health, causing harm and escalating healthcare
costs. Underreporting persists despite ADR Monitoring
Centres (AMCs), necessitating enhanced training, public
education, and integrated drug safety education.
This article delves into the pervasive issue of
underreporting ADEs, exploring its extent and
underlying factors. Analyzing the current state is crucial
for developing potential solutions to bolster ADE
reporting and advance patient safety. ADR identification
methods are categorized into combined, active, and
passive strategies. Combined methods integrate various
approaches comprehensively. Active methods, using
computerized reporting and medical note reviews,
exhibit reasonable detection rates. Passive methods,
specifically spontaneous reporting, reveal lower rates
due to workflow interruptions and lack of knowledge.
Underreporting factors span fear-based, knowledge-
based, system-based, and organizational-based elements.
Fear of adverse consequences fosters a culture of silence,
hindering comprehensive reporting.
Rational solutions involve establishing a global
consensus, educational interventions, improving
electronic reporting systems, and exploring alternative
data sources. Continuous efforts are imperative to
enhance knowledge, attitudes, and reporting practices,
ultimately improving medication safety and
patient care outcomes.
Keywords :
Underreporting, Healthcare Professional, Solutions, Adverse Drug Reaction.
