Understanding How Antiepileptic Drug Side Effects Influence Quality of Life in Epilepsy


Authors : Alshada Sharf; G. Vimal Raj; Thomas Jude Rodriguez; S. Jothi Mani; Dr. Arul Prakasam K

Volume/Issue : Volume 10 - 2025, Issue 6 - June


Google Scholar : https://tinyurl.com/mu84xj3w

DOI : https://doi.org/10.38124/ijisrt/25jun117

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Antiepileptic drugs (AEDs) are the cornerstone of epilepsy management, yet their adverse effects (AEs) often compromise patient well‐being. These AEs range from mild somatic symptoms to severe psychiatric and cognitive disturbances, significantly impacting quality of life (QoL) regardless of seizure control. This review compiles current evidence on the spectrum of AED‐related AEs, their influence on QoL, and the differential profiles of older versus newer AEDs. It also examines psychosocial outcomes and strategies to mitigate these impacts—insights essential for personalised treatment planning.

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Antiepileptic drugs (AEDs) are the cornerstone of epilepsy management, yet their adverse effects (AEs) often compromise patient well‐being. These AEs range from mild somatic symptoms to severe psychiatric and cognitive disturbances, significantly impacting quality of life (QoL) regardless of seizure control. This review compiles current evidence on the spectrum of AED‐related AEs, their influence on QoL, and the differential profiles of older versus newer AEDs. It also examines psychosocial outcomes and strategies to mitigate these impacts—insights essential for personalised treatment planning.

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