Volatile Liquid Mosquito Repellant Induced Psychosis: A Rare Psychiatric Presentation


Authors : Dr. Pranav Wasadikar; Dr. M. Ramkumar

Volume/Issue : Volume 10 - 2025, Issue 3 - March


Google Scholar : https://tinyurl.com/mpkbh3z3

Scribd : https://tinyurl.com/msbnfpx3

DOI : https://doi.org/10.38124/ijisrt/25mar1629

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Abstract : This case highlights a rare instance of psychosis induced by occupational exposure to diethyl phthalate, a primary component in certain liquid mosquito repellents. A 48-year-old male exhibited increased irritability, suspiciousness towards family members, and forgetfulness. He had a three-year history of occupational exposure to volatile liquid mosquito repellents containing predominantly diethyl phthalate. Comprehensive evaluations ruled out other causes. MRI revealed toxic encephalopathy. Mental status examination showed anterograde amnesia, persecutory delusions, irritable affect, impaired judgment, and lack of insight. The patient was treated with Sodium Valproate (1g) and Olanzapine (20mg), leading to significant improvement. This case underscores the neuropsychiatric risks associated with prolonged occupational exposure to diethyl phthalate and highlights the need for further research and awareness.

Keywords : Diethyl Phthalate, Occupational Exposure, Toxic Encephalopathy, Psychosis, Case Report.

References :

  1. Safarpour S, Ghasemi-Kasman M, Safarpour S, Darban YM. Effects of Di-2-Ethylhexyl Phthalate on central nervous system functions: A narrative review. Curr Neuropharmacol. 2022;20(4):766-76.
  2. Weaver JA, Beverly BEJ, Keshava N, Mudipalli A, Arzuaga X, Cai C, et al. Hazards of diethyl phthalate (DEP) exposure: A systematic review of animal toxicology studies. Environ Int. 2020;145:105848.
  3. EPA. Diethyl Phthalate (DEP) Factsheet. https://www.epa.gov/sites/default/files/2015-04/documents/diethylphathalate.pdf
  4. CDC. Diethyl Phthalate: Occupational Exposure. https://wwwn.cdc.gov/TSP/PHS/PHS.aspx?phsid=601&toxid=112

This case highlights a rare instance of psychosis induced by occupational exposure to diethyl phthalate, a primary component in certain liquid mosquito repellents. A 48-year-old male exhibited increased irritability, suspiciousness towards family members, and forgetfulness. He had a three-year history of occupational exposure to volatile liquid mosquito repellents containing predominantly diethyl phthalate. Comprehensive evaluations ruled out other causes. MRI revealed toxic encephalopathy. Mental status examination showed anterograde amnesia, persecutory delusions, irritable affect, impaired judgment, and lack of insight. The patient was treated with Sodium Valproate (1g) and Olanzapine (20mg), leading to significant improvement. This case underscores the neuropsychiatric risks associated with prolonged occupational exposure to diethyl phthalate and highlights the need for further research and awareness.

Keywords : Diethyl Phthalate, Occupational Exposure, Toxic Encephalopathy, Psychosis, Case Report.

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