Authors :
Maha Lhaloui; Hassnaa Sarhane; Youssef Essebbagh; Nada Essaidi; Nermine Jilal; Yasser Lemaati; Amina Etber; Amina Lakhdar; Najia Zraidi; Aziz Baydada
Volume/Issue :
Volume 10 - 2025, Issue 7 - July
Google Scholar :
https://tinyurl.com/fhhndpdn
Scribd :
https://tinyurl.com/mkkur4vu
DOI :
https://doi.org/10.38124/ijisrt/25jul1072
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Note : Google Scholar may take 30 to 40 days to display the article.
Abstract :
Vulvar cancers are rare tumors that are often treated late due to symptoms being overlooked by patients. Surgery
remains the best therapeutic option. Concurrent radiochemotherapy, conservative surgery with sentinel lymph node biopsy
are used in early-stage cases.On the other hand, radical surgery and lymph node dissection are the preferred treatments for
advanced stages, although they carry a high risk of morbidity.
Keywords :
Vulvar Cancer, Diagnostic Stages, Vulvectomy, Chemotherapy, Sentinel Node, Vulvar Radiotherapy.
References :
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- Douay-Hauser N, Akerman G, Tulpin L, Morel O, Malartic C, Desfeux P, et al.
- Smith JS, Backes DM, Hoots BE, Kurman RJ, Pimenta JM. Human papillomavirus type-distribution in vulvar and vaginal cancers and their associated precursors. Obstet Gynecol 2009;113:917—24.
- Leroy JL, Vinatier D, Collier F, Thomas P. Diagnostic d’une néoplasie intraépithéliale vulvaire (VIN). Gynecol Obstet Fertil 2008;36:190—9.
- Carter JS, Downs LS. Vulvar and vaginal cancer. J Obstet Gynecol Clin North Am 2012;39:213—31.
- Mulvany NJ, Allen DG. Differentiated intraepithelial neoplasia of the vulva. Int J Gynecol Pathol 2008;27: 125—35.
- Coleman MP, Gatta G, Verdecchia A, Esteve J, Sant M, Storm H, et al. EUROCARE-3 summary: cancer survival in Europe at the end of the 20th century. Ann Oncol 2003;14:v128—49.
- Trétarre B, Sauvage M, Molinié F, Aude AM, Danzon A, Guizard AV, et al. Vulve et vagin. In: Survie des patients atteints de cancer en France. Étude des registres du réseau FRANCIM. Paris: Springer-Verlag; 2007. p. 233—40.
- Gould N, Kamelle S, Tillmanns T, Scribner D, Gold M, Walker J, et al. Predictors of complications after inguinal lymphadenectomy. Gynecol Oncol 2001;82:329—32.
- Querleu D, Bonnier P, Morice P, Narducci F, Lhomme C, Haie-Meder C, et al. Prise en charge initiale des cancers gynécologiques : référentiels de la Société franc¸aise d’oncologie gynécologique (SFOG). Gynecol Obstet Fertil 2008;36:338—52
- Blake P. Radiotherapy and chemoradiotherapy for carcinoma of the vulva. Best Pract Res Clin Obstet Gynaecol 2003;17: 649—61.
- Sanguin, S.; Daraï, E.; Brzakowski, M.; Gondry, J.; Fauvet, R. Cancer de la vulve : enquête de pratique de la prise en charge chirurgicale en France. Faut-il se diriger vers des centres de références ?
- Selman TJ, Luesley DM, Acheson N, Khan KS, Mann CH. A systematic review of the accuracy of diagnostic tests for inguinal lymph node status in vulvar cancer. Gynecol Oncol 2005;99:206—14
- Deppe G, Mert I, Belotte J, Winer IS. Chemotherapy of vulvar cancer: a review. Wien Klin Wochenschr 2013;125(6):119–28
- Baiocchi G, Rocha RM. Vulvar cancer surgery. Curr Opin Obstet Gynecol 2014;26(1):9–17.
- Oonk MHM, Planchamp F, Baldwin P, Bidzinski M, Brännström M, Landoni F, et al. European Society of Gynaecological Oncology Guidelines for the management of patients with vulvar cancer. Int J Gynecol Cancer 2017;27(4):832–7.
- Deppe G, Mert I, Winer IS. Management of squamous cell vulvar cancer: a review. J Obstet Gynaecol Res 2014;40(5):1217–25. http://dx.doi.org/10.1111/jog.12352 [Epub 2014 Apr 21.. PMID: 24750413].
- Klapdor R, Hillemanns P, Wölber L, Jückstock J, Hilpert F, de Gregorio N, et al. Outcome after sentinel lymph node dissection in vulvar cancer: a subgroup analysis of the AGO-CaRE1 study. Ann Surg Oncol 2017;24(5):1314–21.
Vulvar cancers are rare tumors that are often treated late due to symptoms being overlooked by patients. Surgery
remains the best therapeutic option. Concurrent radiochemotherapy, conservative surgery with sentinel lymph node biopsy
are used in early-stage cases.On the other hand, radical surgery and lymph node dissection are the preferred treatments for
advanced stages, although they carry a high risk of morbidity.
Keywords :
Vulvar Cancer, Diagnostic Stages, Vulvectomy, Chemotherapy, Sentinel Node, Vulvar Radiotherapy.