This study focused on the community of macroinvertebrates and their distribution in the Adofi River receiving cassava effluents. Samples for physicochemical analysis of water parameters and macroinvertebrates were collected bi-monthly for three months at three different stations (I, II, III) in Adofi River. The results of the physicochemical analysis did not reveal any significant difference in the values of the parameters measured between the three stations at (p≤0.05). Themacroinvertebrate community recorded in Adofi River was low and was dominated by Odonata.The principal coordinate analysis revealed that Odonata and Coleoptera positively impacted Station III along the principal axis 1. The dominance of Odonata and coleoptera in River Adofi, as well as the absence of pollution sensitive EPT-groups, indicated that fermentation of cassava in Adofi river is a serious Stressor to the Environment, therefore creating an urgent need for watermanagers to develop strategies to improve the water quality of Adofi River as well as manage itsfisheries potential

Keywords : Adofi, River, Physico-Chemical, Diversity, Index.