Authors :
Yogeshwaran M; Madhumethra R G; Dharshana K; Dr. Selvamani P; Dr. Latha S
Volume/Issue :
Volume 8 - 2023, Issue 11 - November
Google Scholar :
https://tinyurl.com/yc43zz42
Scribd :
https://tinyurl.com/4atpprcd
DOI :
https://doi.org/10.5281/zenodo.10224242
Abstract :
Nanoparticle coating have great potential in
biochemistry and medical science. It can provide
biocompatibility, prolonged blood circulation and
possibly resolve the drug resistance cancer problem. This
article delves into the intricate realm of protein corona
formation on nanoparticles, nanoscale metal-organic
frameworks (nMOFs) as drug delivery systems, and the
challenges associated with nanomedicine. It explores the
impact of preparation techniques on the precision and
interpretation of biomolecular/protein corona, shedding
light on methods, causes of methodological problems,
and typical misunderstandings. Additionally, the article
investigates the potential of genetically engineered
biomimetic nanoparticles for altering intracellular
localization and enhancing payload delivery. It discusses
the importance of accurate characterization, stability,
and controlled release of nanoparticles for effective drug
delivery. Furthermore, it explores antibacterial coatings,
silver nanoparticle coatings, and coatings made of
magnetic nanoparticles, offering insights into their
applications and biocompatibility. This holistic
examination underscores the critical need for
methodological precision in nanomedicine, with
implications for diagnostics, therapeutics, and future
research endeavor’s.
Keywords :
Nanoscale metal organic framework, protein corona, magnetic nanoparticles, antibacterial coating, silver nanoparticle coating, drug delivery.
Nanoparticle coating have great potential in
biochemistry and medical science. It can provide
biocompatibility, prolonged blood circulation and
possibly resolve the drug resistance cancer problem. This
article delves into the intricate realm of protein corona
formation on nanoparticles, nanoscale metal-organic
frameworks (nMOFs) as drug delivery systems, and the
challenges associated with nanomedicine. It explores the
impact of preparation techniques on the precision and
interpretation of biomolecular/protein corona, shedding
light on methods, causes of methodological problems,
and typical misunderstandings. Additionally, the article
investigates the potential of genetically engineered
biomimetic nanoparticles for altering intracellular
localization and enhancing payload delivery. It discusses
the importance of accurate characterization, stability,
and controlled release of nanoparticles for effective drug
delivery. Furthermore, it explores antibacterial coatings,
silver nanoparticle coatings, and coatings made of
magnetic nanoparticles, offering insights into their
applications and biocompatibility. This holistic
examination underscores the critical need for
methodological precision in nanomedicine, with
implications for diagnostics, therapeutics, and future
research endeavor’s.
Keywords :
Nanoscale metal organic framework, protein corona, magnetic nanoparticles, antibacterial coating, silver nanoparticle coating, drug delivery.
