The present work aims to optimize the formulation of a paper from the cellulose extracted from water hyacinth. The major concern was to define the best proportions of the constituents used in the formulation of the paper in order to obtain a precise paper. To this end, 13 paper samples were made from cellulose, starch, Tio2 and kaolin. The objectives are to define the parameters influencing the quality of the paper, to formulate tests to understand the role played by each of these parameters, to develop an optimal mathematical model by using the mixing plan method. Because it offers the advantage of considerably reducing the number of experiments. We have defined an experimentation matrix taking into account all the factors necessary for the formulation of our paper. The main response functions being: the moisture content or water content and the mass. We obtained quadratic models of each answer and checked the validity of these by a global, mathematical and statistical analysis of the

Keywords : cellulose, formulation, kaolin, mixtures, extraction, water hyacinth