Authors : Vedanti Bhoir; Riya Bhoir; Chanchal Bhoir; Saloni Bhoir; Sneha Bhoir; Saurabh Borde; Choudhary Sidra Eram Shamim Ahmed

Volume/Issue : Volume 9 - 2024, Issue 6 - June

Google Scholar : https://tinyurl.com/3yfyad2d

Scribd : https://tinyurl.com/344b2pn9

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUN280

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : As we all know that traditional herbs and plants have any medicinal benefits and used in treatment of wide variety of diseases. Panner Doda is traditional plant which is used in treatment of many diseases such as diabetes, wound healing menstrual disorders, etc. Panner phool (withania Coagulans) have medicinal properties to control diabetes mellitus type 2. Panner dodi is available in powder form (rarely) but most commonly available as dried phool which is soaked overnight in a water to have maximum benefits to control diabetes. But it hasonly drawn that it is bitter in taste. So oral medicated sweet jelly formulation has a sweet tasteand has an attractive appearance. So, it has become easy to have a medicine by altering its bittertaste and can be given to paediatrics as well as geriatric patients suffering from diabetes mellitus. Paneer Doda (Withania Coagulans Dunal), belonging to the family Solanaceae, is a small bushwhich is widely spread in South Asia. It grows as short shrub (35-75 cm) with central stem. This shrub is common in Afghanistan, East India & Nepal. In India it occurs in Punjab, Rajasthan, Simla, Kumaun and Garhwal. It is commonly known as ‘Indian cheese maker’ or ‘vegetable rennet’ due to coagulant property of leaves and fruits. The berries contain two esterases, free amino acids, fatty oil, an essential oil and alkaloids. The amino acids present areproline, hydroxyproline, valine, tyrosine, aspartic acid, glycine asparagin, cysteine and glutamic acid. A variety of withanolides have been found in the plant which are responsible for its therapeuticproperties. It is widely used in treating diabetes mellitus, nervous exhaustion, disability, insomnia, wasting diseases and failure to thrive in children. The fruits of the plant are reportedto be sedative, emetic, alterative and diuretic. They are also helpful in liver complaints, asthmaand biliousness. Withania coagulans is commonly known as Paneer Dodi belonging to family Solanaceae is a well -known plant in herbal medicinal systems having great potential against diabetic disease by improving the secretion of insulin. It was though worthwhile to explore its application intoour body to treat type-2 diabetes, it acts on the insulin receptors for the better consumption of insulin.

References :

1. Desai, S.B., Narkhede, S.B., Prajapati, U., Patel, D.T., Patel, D.G., Patel, H.H., Patel,
2. H.A. and Patel, I.H., 2023. FORMULATION AND EVALUATION OF HERBAL CAPSULE CONTAINING PANEER DODI AND FENUGREEK FOR THE TREATMENT OF DIABETES. EPRA International Journal of Research and Development (IJRD), 8(5), pp.409-418.
3. Begum, S.A., Sree, V.P., Anusha, V., Veronica, Z.K., Sree, P.V., Prameela, K., Nazeema, M.D. and Padmalatha, K., 2018. Formulation and evaluation of paediatric oral soft jellies of salbutamol sulphate. Research Journal of Pharmacy and Technology, 11(11), pp.4939-4945.
4. Yadav, C., Tangri, S. and Yadav, R., 2018. A review recent advancement in formulation of oral medicated jelly. World J Pharmacy Pharm Sci, 7(7), pp.417-426.
5. https://www.slideshare.net/slideshow/formulation-and-evaluation-of-oral-soft-jelly- containing-ascorbic-acid/266151394
6. https://thepharmapedia.com/pharmaceutical-jellies-pharmacy-notes/pharmacy- notes/#Evaluation Parameters for Oral Jelly.
7. Gupta, P. and Singh, P., 2018. Withania cogulance-A miracle for diabetes. Int. J. Recent Trends Sci. Techn, pp.203-207.
8. Gupta, P.C., 2012. Withania coagulans Dunal-an overview. International Journal of Pharmaceutical Sciences Review and Research, 12(2), pp.68-71.
9. Jhajhria, A. and Kumar, K., 2016. Fenugreek with its medicinal applications. Int. J. Pharm. Sci. Rev. Res, 41(1), pp.194-201.
10. Jyothi, D., Koland, M., Priya, S. and James, J.P., 2017. Formulation of herbal capsule containing Trigonella foenum-graecum seed extract for the treatment of diabetes. Journal of Young Pharmacists, 9(3), p.352.
11. Khan, A.I., Gupta, S. and Gautam, G., 2019. Physicochemical and Phytochemical Screening of Fenugreek (Trigonella foenum greacum) Indian Medicinal Plant.
12. Khandelwal, K., 2008. Practical pharmacognosy. Pragati Books Pvt. Ltd.
13. Agarwal, N., Raghav, P.K. and Singh, R.P., 2014. A Promising Therapeutic Agent. Int. J. Green Herb. Chem, 3, pp.701-711.
14. Upadhyay, B.N. and Gupta, V., 2011. A clinical study on the effect of Rishyagandha (Withania coagulans) in the management of Prameha (Type II Diabetes Mellitus). AYU (An international quarterly Journal of research in Ayurveda), 32(4), pp.507-511.