In this article we propose specific answers to three of the most persistent questions: i- Do probabilities and statistics belong to physics or mathematics? iiFollowed by the related question, does nature operate in 3D geometry plus time as an external controller or more specifically, does it operate in the inseparable 4D unit space where time is woven? iii-Lagrange multipliers: Is it just a classic mathematical trick that we can do without? The answers to these questions are all interconnected. Here we could say that the modern definition of probability in the transition matrix B is an interconnected thing of the three topics. Imagination is the first important common factor in mathematics, physics and especially in the probability of transition in 4D space. In a breakthrough technique, B-matrix chains are used in this article to numerically solve single, double, and triple (Hypercube) integrals as a successful preliminary answer to this question. In fact, it is the natural continuation of the success of B-chains in solving the general case of time-dependent partials of differential equations with Dirichlet Arbitrary BC and arbitrary initial conditions that have been explained in previous articles.